2-Chloro-1-fluoro-4-nitrobenzene → 2-Chloro-4-nitrophenyl 2-thienyl sulphide

HRID 399471Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[CH:5]=[CH:6][C:7]=1F.[S:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[SH:17]>>[S:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[S:17][C:7]1[CH:6]=[CH:5][C:4]([N+:9]([O-:11])=[O:10])=[CH:3][C:2]=1[Cl:1]

Participants

Reactant 2

HCID 676882-Chloro-1-fluoro-4-nitrobenzene

HCID 5226742-Thiophenethiol

Product 1

HCID 189675792-Chloro-4-nitrophenyl 2-thienyl sulphideYield 32%

Procedure

Using an analogous procedure to that described in the first paragraph of the portion of Example 8 which is concerned with the preparation of starting materials, 3-chloro-4-fluoronitrobenzene was reacted with 2-thiophenethiol to give 2-chloro-4-nitrophenyl 2-thienyl sulphide in 32% yield.

Sources & evidence

ORD record: ord-f68f3c549d444d70bd946afdde28bb94
Source dataset: uspto-grants-1998_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05821246

Reaction notes

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