HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 6-Acetoxy-4-chloroquinazoline hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Oxo-1,4-dihydroquinazolin-6-yl acetate | HCID 135584220 | — |
| Product | 6-Acetoxy-4-chloroquinazoline hydrochloride | HCID 18967623 | — |
Reaction Steps
Using an analogous procedure to that described in the first paragraph of the portion of Example 1 which is concerned with the preparation of starting materials, 6-acetoxyquinazolin-4-one was reacted with thionyl chloride to give 6-acetoxy-4-chloroquinazoline hydrochloride which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05821246 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-b47cba7530ca4415aa319bcf55257638 |
| Source note | uspto-grants-1998_10 |