HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-N,N-dimethylethylamine → HCID 18967627, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-N,N-dimethylethylamine | HCID 7901 | — |
| Reactant | HCID 18967588 | HCID 18967588 | — |
| Product | HCID 18967627 | HCID 18967627 | 47% |
Reaction Steps
Using an analogous procedure to that described in Example 37, 6-hydroxy-7-methoxy-4-[3-methyl-4-(2-pyridylmethoxy)anilino]quinazoline was reacted with 2-dimethylaminoethyl chloride to give 6-(2-dimethylaminoethoxy)-7-methoxy-4-[3-methyl-4-(2-pyridylmethoxy)anilino]quinazoline in 47% yield, m.p. 125°-126° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05821246 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-318dd12ed00e44678e86596931e9a4ce |
| Source note | uspto-grants-1998_10 |