Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 399561Generated: October 30, 2026

Morpholine → HCID 178507838, compound

https://huagongshe.com/reaction/399561

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
ReactantHCID 178507839HCID 178507839—
SolventTriethylamineHCID 8471—
ProductHCID 178507838HCID 178507838—

Reaction Steps

Prepared from 4-[(4-amino-3,5-dichlorophenyl)amino]-6-[(trans-4-carboxycyclohexyl)amino]pyrimido[5,4-d]pyrimidine by reaction with O-(benzotriazol-1-yl)-N,N,N',N',-tetramethyluronium tetrafluoroborate, triethylamine and morpholine. Melting point: 204°-207° C.; Rf : 0.53 (silica gel; petroleum ether/ethyl acetate/methanol=10:10:4)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05821240
Source datasetuspto-grants-1998_10
ORD IDord-29392faa374b4240956aa3c28c14ea95
Source noteuspto-grants-1998_10