HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 18967328, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | HCID 18946128 | HCID 18946128 | — |
| Product | HCID 18967328 | HCID 18967328 | — |
Reaction Steps
Prepared from 4-[(3-chloro-4-fluorophenyl)amino]-6-[4-(4-piperidinyl)-1-piperidinyl]pyrimido[5,4-d]pyrimidine by reductive amination with formaldehyde and sodium cyanoborohydride. Melting point: 159°-162° C.; Rf : 0.58 (alumina; petroleum ether/ethyl acetate/methanol=10:10:1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05821240 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-afd63b7bb49349eab58a4cb7096eee84 |
| Source note | uspto-grants-1998_10 |