HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 18946229, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Reactant | HCID 18967316 | HCID 18967316 | — |
| Product | HCID 18946229 | HCID 18946229 | — |
Reaction Steps
Prepared from 4-[(3-chloro-4-fluorophenyl)amino]-6-[1-tert-butyloxycarbonyl-4-piperidinylamino]pyrimido[5,4-d]pyrimidine by reaction with trifluoroacetic acid and subsequent reaction with cyanogen bromide. Melting point: 245°-247° C.; Rf : 0.59 (silica gel; petroleum ether/ethyl acetate/methanol=10:10:3)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05821240 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-bf7dfb838ba546d6a84664e7c36fc25d |
| Source note | uspto-grants-1998_10 |