HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 18946135, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Dimethylcarbamoyl Chloride | HCID 6598 | — |
| Reactant | HCID 18967316 | HCID 18967316 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 18946135 | HCID 18946135 | — |
Reaction Steps
Prepared from 4-[(3-chloro-4-fluorophenyl)amino]-6-[1-tertbutyloxycarbonyl-4-piperidinylamino]pyrimido[5,4-d]pyrimidine by reaction with trifluoroacetic acid and subsequent reaction with dimethylcarbamoyl chloride and triethylamine. Melting point: 187°-188° C.; Rf : 0.59 (alumina; petroleum ether/ethyl acetate/methanol=10:10:2)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05821240 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-97fb371be07d48e3875a4c64b09c1647 |
| Source note | uspto-grants-1998_10 |