Triethylamine → HCID 2822834, compound

HRID 399592Notes

Reaction equation

HRID 399592 reaction equation
[CH2:1]([N:8]([C:22](=[O:26])[CH2:23][C:24]#[N:25])[C:9]([NH:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([O:20][CH3:21])=[O:19])[CH:13]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(N(CC)CC)C>ClCCl>[NH2:25][C:24]1[N:11]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([O:20][CH3:21])=[O:19])[CH:13]=2)[C:9](=[O:10])[N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[C:22](=[O:26])[CH:23]=1

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 23293703HCID 23293703, compound

Product 1

HCID 2822834HCID 2822834, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1-Benzyl-1-(cyanoacetyl)-3-[3-(methoxycarbonyl)phenyl]urea (3.51 g) was dissolved in dichloromethane (50 ml) and triethylamine (1.52 g) added. The mixture was stirred for one hour at room temperature and the product filtered off and washed with dichloromethane. Yield=3.16 g.

Workup

  1. filtrationthe product filtered off
  2. washwashed with dichloromethane

Sources & evidence

ORD record
ord-c98b7673800c423ab70c75f3ebae4e4f
Source dataset
uspto-grants-1998_10
Patent number
US05821366

Reaction notes

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