HCID 18944905, compound → HCID 54276064, compound

HRID 399724Notes

Reaction equation

HRID 399724 reaction equation
[SH:1][CH:2]([CH2:12][CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-])=O)[CH:16]=1)[CH:3]([P:8](=[O:11])([OH:10])[OH:9])[P:4](=[O:7])([OH:6])[OH:5]>O=[Pt]=O.O>[SH:1][CH:2]([CH2:12][CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([NH2:21])[CH:16]=1)[CH:3]([P:4](=[O:5])([OH:6])[OH:7])[P:8](=[O:9])([OH:10])[OH:11]

Participants

4

Reactant 1

HCID 18944905HCID 18944905, compound

Product 1

HCID 54276064HCID 54276064, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 962WaterSolvent

Procedure

[2-Mercapto-5-(3-nitrophenyl)pentylidene]bis[phosphonic acid] (0.25 mmol), distilled water (75 ml) and PtO2 (0.20 mg) are placed in a 500 ml Parr hydrogenation bottle. The mixture is hydrogenated at room temperature (40 psi) for 6 hours. The solution is filtered through celite and concentrated under reduced pressure. The resultant solid is triturated in acetone and then further dried overnight in a vacuum desiccator.

Workup

  1. customis hydrogenated at room temperature
  2. customfor 6 hours
  3. filtrationThe solution is filtered through celite and
  4. concentrationconcentrated under reduced pressure
  5. customThe resultant solid is triturated in acetone
  6. customfurther dried overnight in a vacuum desiccator

Sources & evidence

ORD record
ord-cf201eff9d114f499eebb603ac9892cb
Source dataset
uspto-grants-1998_10
Patent number
US05824661

Reaction notes

Loading…