反应详情

Jineol of 4.5 mg was dissolved in 2 ml of ethanol, and diazomethane ether solution was slowly dropped to the solution. After the excess of diazomethane and solvent was removed by purging with nitrogen gas, the solution was purified by silicagel chromatography to give 4.2 mg of 3,8-dimethoxy quinoline with 80% yield.

1. customAfter the excess of diazomethane and solvent was removed
2. customby purging with nitrogen gas
3. customthe solution was purified by silicagel chromatography