反应详情

10% Palladium on carbon (0.25 g) was added to the solution of methyl 3-[2-((E)-2-benzyloxycarbonylethenyl)pyrrol-1-yl]benzoate (2.5 g) in methanol (50 ml) and the mixture was subjected to catalytic reduction at the ambient temperature under atmospheric pressure. The catalyst was removed by filtration and the filtrate was evaporated in vacuo. The residue was triturated with diisopropyl ether to give methyl 3-[2-(2-carboxyethyl)pyrrol-1-yl]benzoate (1.02 g).

1. customwas subjected to catalytic reduction at the ambient temperature under atmospheric pressure
2. customThe catalyst was removed by filtration
3. customthe filtrate was evaporated in vacuo
4. customThe residue was triturated with diisopropyl ether