methyl 3-[2-((E)-2-benzyloxycarbonylethenyl)pyrrol-1-yl)benzoate → Methyl 3-[2-(2-carboxyethyl)pyrrol-1-yl]benzoate

Participants

Reaction Steps

10% Palladium on carbon (0.25 g) was added to the solution of methyl 3-[2-((E)-2-benzyloxycarbonylethenyl)pyrrol-1-yl]benzoate (2.5 g) in methanol (50 ml) and the mixture was subjected to catalytic reduction at the ambient temperature under atmospheric pressure. The catalyst was removed by filtration and the filtrate was evaporated in vacuo. The residue was triturated with diisopropyl ether to give methyl 3-[2-(2-carboxyethyl)pyrrol-1-yl]benzoate (1.02 g).

Provenance & Evidence