Hydrogen iodide → HCID 86753239, compound

HRID 400069Notes

Reaction equation

HRID 400069 reaction equation
Cl.[CH3:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1([C:15]([NH2:17])=[O:16])[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1.[IH:18]>C(O)C>[IH:18].[CH3:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1([C:15]([NH2:17])=[O:16])[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]1

Participants

4

Reactant 2

HCID 24841Hydrogen iodideHCID 67560943HCID 67560943, compound

Product 1

HCID 86753239HCID 86753239, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Combine 4-(methyl-phenyl)-piperidine-4-carboxylic acid amide hydrochloride (10 mmol) and an aqueous solution of hydriodic acid (57%, 15 mmol) in ethanol (20 mL). Heat to reflux. After 30 minutes, cool to ambient temperature and evaporate in vacuo to give the title compound.

Workup

  1. temperatureHeat to reflux
  2. customevaporate in vacuo

Sources & evidence

ORD record
ord-c67316bdcfd44ef5a02eb7a512af6369
Source dataset
uspto-grants-1998_10
Patent number
US05824690

Reaction notes

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