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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 400105Generated: October 31, 2026

Phosphorus oxychloride → 2-Chloro-6,7,8,9-tetrahydro-7-(phenylmethyl)-5H-pyrido[2,3-D]azepine

https://huagongshe.com/reaction/400105

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178478868HCID 178478868—
Product2-Chloro-6,7,8,9-tetrahydro-7-(phenylmethyl)-5H-pyrido[2,3-D]azepineHCID 18943403—

Reaction Steps

Prepared by reacting 2-hydroxy-7-benzyl-6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepine dihydrochloride with phosphorus oxychloride at 140° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05827849
Source datasetuspto-grants-1998_10
ORD IDord-26998b13408a4e338091365c1ee5a122
Source noteuspto-grants-1998_10