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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 400109Generated: October 30, 2026

Phosphorus oxychloride → 3-Chloro-7-ethyl-6,7,8,9-tetrahydro-5H-pyrido[3,4-d]azepine

https://huagongshe.com/reaction/400109

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178462500HCID 178462500—
Product3-Chloro-7-ethyl-6,7,8,9-tetrahydro-5H-pyrido[3,4-d]azepineHCID 18943607—

Reaction Steps

Prepared from 3-hydroxy-7-ethyl-6,7,8,9-tetrahydro-5H-pyrido[3,4-d]azepine dihydrochloride by reaction with phosphorus oxychloride at 130° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05827849
Source datasetuspto-grants-1998_10
ORD IDord-0e26e0f32e74465d88d1bc9bae21568f
Source noteuspto-grants-1998_10