Hydroxyamine hydrochloride → 1-benzyl-4-chloro-5-hydroxyiminomethyl-2,3,6,7-tetrahydro-1H-azepine

HRID 400113Notes

Reaction equation

HRID 400113 reaction equation
Cl.[CH2:2]([N:9]1[CH2:15][CH2:14][C:13]([CH:16]=O)=[C:12]([Cl:18])[CH2:11][CH2:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.Cl.[NH2:20][OH:21]>C(O)C>[CH2:2]([N:9]1[CH2:15][CH2:14][C:13]([CH:16]=[N:20][OH:21])=[C:12]([Cl:18])[CH2:11][CH2:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 189435411-benzyl-5-chloro-2,3,6,7-tetrahydro-1H-azepine-4-carbaldehyde hydrochloride

Product 1

HCID 866216731-benzyl-4-chloro-5-hydroxyiminomethyl-2,3,6,7-tetrahydro-1H-azepine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared by reacting 1-benzyl-4-chloro-5-formyl-2,3,6,7-tetrahydro-1H-azepine hydrochloride with hydroxylamine hydrochloride in ethanol at 30° C.

Workup

  1. customPrepared
  2. customat 30° C.

Sources & evidence

ORD record
ord-ab994e9d2b3e4cf0ba7ff85502ef1a00
Source dataset
uspto-grants-1998_10
Patent number
US05827849

Reaction notes

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