Methyl Acrylate → HCID 11636953, compound

Participants

Reaction Steps

A! Methyl acrilate (89 ml, 0.988 mmole) was slowly dropped into a solution of diisopropylamine (27.7 ml, 0.198 mmole) in methanol (300 ml) at -10° C. The reaction mixture was brought to room temperature and stirred for 24 hours, then the solvent and the methyl acrilate in excess were evaporated off thus obtaining 37 g of crude methyl 3-(N,N-diisopropylamino)propionate (quantitative yield) which was directly employed in the next step.

Provenance & Evidence