Methyl Acrylate → HCID 11636953, compound

HRID 400212Notes

Reaction equation

HRID 400212 reaction equation
[C:1]([O:5][CH3:6])(=[O:4])[CH:2]=[CH2:3].[CH:7]([NH:10][CH:11]([CH3:13])[CH3:12])([CH3:9])[CH3:8]>CO>[CH:7]([N:10]([CH2:3][CH2:2][C:1]([O:5][CH3:6])=[O:4])[CH:11]([CH3:13])[CH3:12])([CH3:9])[CH3:8]

Participants

4

Reactant 2

HCID 7294Methyl AcrylateHCID 7912Diisopropylamine

Product 1

HCID 11636953HCID 11636953, compoundYield 99,780.797%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A! Methyl acrilate (89 ml, 0.988 mmole) was slowly dropped into a solution of diisopropylamine (27.7 ml, 0.198 mmole) in methanol (300 ml) at -10° C. The reaction mixture was brought to room temperature and stirred for 24 hours, then the solvent and the methyl acrilate in excess were evaporated off thus obtaining 37 g of crude methyl 3-(N,N-diisopropylamino)propionate (quantitative yield) which was directly employed in the next step.

Workup

  1. customwas brought to room temperature
  2. customthe solvent and the methyl acrilate in excess were evaporated off

Sources & evidence

ORD record
ord-95549129f5c94095b747003632130b96
Source dataset
uspto-grants-1998_10
Patent number
US05827881

Reaction notes

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