HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-7-[2-(2,2-dimethyl-4-trifluoromethyl-[1,3]dioxolan-4-yl)-1,1-dimethylethyl]-2,3-dihydrobenzofuran → 7-(4,4,4-Trifluoro-3-hydroxy-3-hydroxymethyl-1,1-dimethylbutyl)-2,3-dihydrobenzofuran-5-sulfonic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-7-[2-(2,2-dimethyl-4-trifluoromethyl-[1,3]dioxolan-4-yl)-1,1-dimethylethyl]-2,3-dihydrobenzofuran | HCID 57809922 | — |
| Reactant | 7-(4,4,4-Trifluoro-3-hydroxy-3-hydroxymethyl-1,1-dimethyl-butyl)-2,3-dihydrobenzofuran-5-sulfonic acid dimethylamide | HCID 60026666 | — |
| Product | 7-(4,4,4-Trifluoro-3-hydroxy-3-hydroxymethyl-1,1-dimethylbutyl)-2,3-dihydrobenzofuran-5-sulfonic acid amide | HCID 60026740 | — |
Reaction Steps
7-(4,4,4-Trifluoro-3-hydroxy-3-hydroxymethyl-1,1-dimethylbutyl)-2,3-dihydrobenzofuran-5-sulfonic acid amide was prepared from 5-bromo-7-[2-(2,2-dimethyl-4-trifluoromethyl-[1,3]dioxolan-4-yl)-1,1-dimethylethyl]-2,3-dihydrobenzofuran in the same manner as in the preparation of 7-(4,4,4-trifluoro-3-hydroxy-3-hydroxymethyl-1,1-dimethylbutyl)-2,3-dihydrobenzofuran-5-sulfonic acid dimethylamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08741897B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-eb26850167c24797b937f6d5495b49be |
| Source note | uspto-grants-2014_06 |