HCID 178510114, compound → 7-fluoro-N'-hydroxy-3H-benzimidazole-5-carboximidamide

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Reaction Steps

The title compound was prepared following the procedure described for Intermediate 1, step 2, but starting from 7-fluoro-1H-benzimidazole-5-carbonitrile obtained in step 2 (750 mg; 4.65 mmol) as a beige solid (814 mg, 90%). 1H NMR (DMSO-d6) δ 12.88 (bs, 1H), 9.67 (s, 1H), 9.30 (s, 1H), 7.68 (s, 1H), 7.33-7.29 (m, 1H), 5.89 (s, 2H). LC/MS (Method B): 195.1 (M+H)+.

Provenance & Evidence