참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Triethylsilane | HCID 12052 | — |
| 반응물 | 5-tert-Butyl-3-(4-methoxy-benzyl)-7-(3,3,4,4-tetrafluoro-pyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine | HCID 86683345 | — |
| 용매 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | HCID 178441794 | HCID 178441794 | — |
반응 단계
The crude 5-tert-Butyl-3-(4-methoxy-benzyl)-7-(3,3,4,4-tetrafluoro-pyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine was treated with triethylsilane in TFA and heated to 70° C. for 20 h and evaporated. The crude material was used without further purification in the consecutive step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08741906B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_06 |
|---|
| ORD ID | ord-5914a317b2314e9f9a42b02b9067a6b8 |
|---|
| 출처 메모 | uspto-grants-2014_06 |
|---|
