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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 40146Generated: October 29, 2026

3,4-Difluorobenzylamine → 1-Benzyl-N-(3,4-difluorobenzyl)-5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxamide

https://huagongshe.com/reaction/40146

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DifluorobenzylamineHCID 123572—
ReactantHCID 59762356HCID 59762356—
Product1-Benzyl-N-(3,4-difluorobenzyl)-5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxamideHCID 59762401—

Reaction Steps

The title compound was prepared from 1-benzyl-5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxylic acid (Compound 170) and 3,4-difluorobenzylamine by General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524917B2
Source datasetuspto-grants-2013_09
ORD IDord-9ea5ec2fa1d94314a853327d647639a1
Source noteuspto-grants-2013_09