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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 401461Generated: October 26, 2026

6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde → HCID 86670609, compound

https://huagongshe.com/reaction/401461

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromoimidazo[1,2-a]pyridine-3-carbaldehydeHCID 21345676—
Reactant[5-(Trifluoromethyl)pyridin-3-yl]boronic acidHCID 45158900—
ProductHCID 86670609HCID 8667060948%

Reaction Steps

The title compound was prepared by following the procedure as described for Intermediate 1 using 6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde and 5-(trifluoromethyl)pyridin-3-ylboronic acid. Yield: 48%; 1H NMR (DMSO-d6; 300 MHz): δ 10.04 (s, 1H), 9.71 (s, 1H), 9.27 (s, 1H), 9.07 (s, 1H), 8.62 (s, 2H), 8.16-8.19 (dd, 1H, J=1.8&9.3 Hz), 8.03-8.04 (d, 1H, J=9.3 Hz); MS: m/z 292 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08741932B2
Source datasetuspto-grants-2014_06
ORD IDord-30ff643f570a46b5bcd3b6e14e83b14f
Source noteuspto-grants-2014_06