反应详情

To a solution of compound 1c (15.15 g, 53.69 mmol) in CH2Cl2 (60 mL) was added trifluoroacetic acid (18 mL) at room temperature. The mixture was stirred at room temperature for 18 h. The solvent was removed by evaporation. Ether (100 mL) was added to the residue. The white solid was collected by filtration, washed with ether, and dried under vacuum. The crude compound 1d was used in the next reaction without further purification. MS m/z (M+H+) 183.1.

1. customThe solvent was removed by evaporation
2. additionEther (100 mL) was added to the residue
3. filtrationThe white solid was collected by filtration
4. washwashed with ether
5. customdried under vacuum
6. customThe crude compound 1d was used in the next reaction without further purification