2,6-Difluorobenzenesulfonyl chloride → HCID 24830786, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2′-Methyl-5′-oxazol-2-yl-biphenyl-4-ylamine (c) (30 mg, 0.12 mmol) in MeOH (2 mL) was added 2,6-difluorobenzene sulfonyl chloride (30 μL, 0.22 mmol). The reaction was heated to 80° C. for 2 hr before the solvent was removed. Column chromatography afforded Compound 1 (28 mg, 55%).

Provenance & Evidence