HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)-4-methyl-1H-1,2,3-triazole-5-carbaldehyde → (1-(2-Fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)-4-methyl-1H-1,2,3-triazole-5-carbaldehyde | HCID 19914653 | — |
| Reactant | 1-(2-fluorophenyl)-4-methyl-1H-1,2,3-triazole-5-carbaldehyde | HCID 86664766 | — |
| Product | (1-(2-Fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methanol | HCID 67498340 | 75% |
Reaction Steps
As described for example 60e, 1-(2-fluorophenyl)-4-methyl-1H-1,2,3-triazole-5-carbaldehyde (469 mg, 2.19 mmol), instead of 3-(4-fluoro-phenyl)-5-methyl-3H-[1,2,3]triazole-4-carbaldehyde, was converted to the title compound (339 mg, 75%) which was obtained as a white solid. MS: m/e=208.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08742097B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-0d2409a711a04fa3ab5fc1c26d590186 |
| Source note | uspto-grants-2014_06 |