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HRID402970

反应详情

EQUATION

反应方程式

HRID 402970 的结构方程式

REACTANTS

反应物

2
结构：CS(C)=O
HCID679

Dimethyl sulfoxide

C2H6OS

结构：Br.NC(CCBr)C(=O)O
HCID13877992

2-Amino-4-bromobutanoic acid--hydrogen bromide (1/1)

C4H9Br2NO2

PRODUCTS

生成物

2
结构：CSCC[C@H](N)C(=O)O
HCID6137

L-Methionine

C5H11NO2S

收率 82%
结构：N[C@@H](CCO)C(=O)O
HCID12647

2-amino-4-hydroxybutanoic acid

C4H9NO3

收率 2.6%

PROCEDURE

实验过程

4-Bromo-2-aminobutanoic acid hydrobromide (1 eq.) was treated with sodium methane thiolate (3.2 eq.) in DMSO (25 eq.) at 80° C. for 1 hour. Methionine (82% yield) and homoserine (2.6% yield) were obtained.