HCID 71766083, compound → N-[6-Chloro-4-(2-methoxy-pyridin-3-yl)-pyridazin-3-yl]-3-methanesulfonyl-N-methyl-5-trifluoromethyl-benzamide

Participants

Role	Name	HCID	Charge
Reactant	HCID 71766083	HCID 71766083	—
Reactant	6-chloro-4-(2-methoxypyridin-3-yl)-N-methylpyridazin-3-amine	HCID 86698479	—
Solvent	Ethylacetate heptane	HCID 21899848	—
Product	N-[6-Chloro-4-(2-methoxy-pyridin-3-yl)-pyridazin-3-yl]-3-methanesulfonyl-N-methyl-5-trifluoromethyl-benzamide	HCID 71766227	—

Reaction Steps

The title compound was prepared in analogy to example 1, from [6-chloro-4-(2-methoxy-pyridin-3-yl)-pyridazin-3-yl]-methyl-amine and 3-methanesulfonyl-5-trifluoromethyl-benzoic acid (example 1, intermediate d) after a reaction time of 27 hours and using a gradient of n-heptane:ethyl acetate (100:0 to 20:80) for the chromatographic purification. Light yellow solid (10%). MS (ESI+): m/z=501.060 ([M+H]+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08748434B2
Source dataset	uspto-grants-2014_06
ORD ID	ord-baefce9766ba4ec6b9ca75ed02bbb744
Source note	uspto-grants-2014_06