HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Methoxypyridin-3-yl)boronic acid → 6-Chloro-4-(2-methoxypyridin-3-yl)pyridazin-3-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Methoxypyridin-3-yl)boronic acid | HCID 2762709 | — |
| Reactant | 3-Amino-4-bromo-6-chloropyridazine | HCID 22024419 | — |
| Product | 6-Chloro-4-(2-methoxypyridin-3-yl)pyridazin-3-ylamine | HCID 86698480 | — |
Reaction Steps
The title compound was prepared in analogy to example 1, intermediate b, from 4-bromo-6-chloropyridazin-3-amine (CAS RN 446273-59-2) and 2-methoxypyridine-3-boronic acid (CAS RN 163105-90-6) after a reaction time of 18 hours. Brown solid (49%). MS (ESI+): m/z=237.054 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748434B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-70da0f2f0f8a4a0f83c8784e128cb599 |
| Source note | uspto-grants-2014_06 |