1-Benzyl-4-(1-methyl-1H-tetrazol-5-YL)piperidine → 4-(1-methyl-1H-tetrazol-5-yl)-piperidine

Participants

Reaction Steps

Pd(OH)2 (20% on C, 30 mg) was added to a solution of 1-benzyl-4-(1-methyl-1H-tetrazol-5-yl)-piperidine (37) (150 mg, 0.58 mmol) in 15 ml of ethanol and the mixture was hydrogenated at 4-5 bar H2 at 50° C. for 16 h. The catalyst was filtered off and the solvent was evaporated to give 38 as a colorless solid.

Provenance & Evidence