HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzonitrile, 4-isothiocyanato- → HCID 131731455, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzonitrile, 4-isothiocyanato- | HCID 17626 | — |
| Reactant | (S)-Methyl 2-(6-(4-(3-(2-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 53303391 | — |
| Reactant | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| Product | HCID 131731455 | HCID 131731455 | — |
Reaction Steps
The compound of example 67 was prepared analogous to compound of example 51 by reaction of compound of example 6 with 4-cyanophenyl isothiocyanate. The compound of example 67 was used directly without isolation for the preparation of compound of example 66.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-d35a9f11eb13423aa793f31a0c6e118a |
| Source note | uspto-grants-2014_06 |