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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403769Generated: October 30, 2026

(S)-3-Methyl-2-(1-oxo-6-(4-(phenylsulfonamido)phenyl)isoindolin-2-yl)butanoic acid → (S)-3-Methyl-2-(1-oxo-6-(4-(phenylmethylsulfonamido)phenyl)isoindolin-2-yl)butanoic acid

https://huagongshe.com/reaction/403769

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-Methyl-2-(1-oxo-6-(4-(phenylsulfonamido)phenyl)isoindolin-2-yl)butanoic acidHCID 67306729—
Reactant(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(phenylmethylsulfonamido)phenyl)isoindolin-2-yl)butanoateHCID 131731464—
Product(S)-3-Methyl-2-(1-oxo-6-(4-(phenylmethylsulfonamido)phenyl)isoindolin-2-yl)butanoic acidHCID 6730742096%

Reaction Steps

The compound of example 94 was prepared analogous to compound of example 78 by hydrolysis of compound of example 93.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-7b9b79fed55b4faf833b83dee0f44320
Source noteuspto-grants-2014_06