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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403832Generated: October 25, 2026

5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl chloride → HCID 123143580, compound

https://huagongshe.com/reaction/403832

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl chlorideHCID 2795466—
Reactant(S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123625862—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
ProductHCID 123143580HCID 12314358076%

Reaction Steps

The compound of example 175 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 5,5,8,8-tetramethyl-5,6,7,8-tetra hydronaphthalene-2-carbonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-e1fc3d8b59c24374b434c357172316a0
Source noteuspto-grants-2014_06