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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403853Generated: October 25, 2026

6-(Trifluoromethyl)nicotinoyl chloride → HCID 131731497, compound

https://huagongshe.com/reaction/403853

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(Trifluoromethyl)nicotinoyl chlorideHCID 2777557—
Reactant(S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123625862—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
ProductHCID 131731497HCID 13173149765%

Reaction Steps

The compound of example 210 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 6-trifluoromethyl nicotinoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-ebf32e4aadf04a37a5abeef183fbf577
Source noteuspto-grants-2014_06