HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 53303514, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | (S)-Methyl 2-(5-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731499 | — |
| Product | HCID 53303514 | HCID 53303514 | — |
Reaction Steps
The compound of example 223 (0.250 g, 0.0073 mol) was taken in dichloromethane (5 mL) to which pyridine (0.174 g, 0.00219 mol) was added and stirred for 5 min. To this reaction mixture, benzene sulfonyl chloride was added and the reaction mixture was stirred for about 16 h. After completion of the reaction, the solvent was evaporated to obtain the title compound, which was directly used for preparation of compound of example 285.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-9c5c830b77d448f7aabed6f891dcb910 |
| Source note | uspto-grants-2014_06 |