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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403944Generated: October 27, 2026

Methyl 2-amino-2-phenylacetate hydrochloride → (S)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-2-phenylacetate

https://huagongshe.com/reaction/403944

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-2-phenylacetate hydrochlorideHCID 12247454—
Reactant(R)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731530—
Product(S)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-2-phenylacetateHCID 131731532—

Reaction Steps

The compound of example 344 was prepared analogous to compound of example 329 by reaction of the compound of example 328 and 2-phenyl glycine methyl ester hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-7846447503074544bf04c858349ea2cb
Source noteuspto-grants-2014_06