HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-Methyl-2-(1-oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)iso indolin-2-yl)butanoic acid → (S)-2-(1-Oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)-2-phenylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-Methyl-2-(1-oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)iso indolin-2-yl)butanoic acid | HCID 67306771 | — |
| Reactant | (S)-Methyl 2-(1-oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)-2-phenylacetate | HCID 131731533 | — |
| Product | (S)-2-(1-Oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)-2-phenylacetic acid | HCID 67305999 | 82% |
Reaction Steps
The compound of example 346 was prepared analogous to compound of example 331 by hydrolysis of the compound of example 345.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-18cc7fe425b44af8940004cfae5695ac |
| Source note | uspto-grants-2014_06 |