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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403965Generated: October 25, 2026

Methyl 1-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)cyclopentanecarboxylate → 1-(1-Oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)cyclopentanecarboxylic acid

https://huagongshe.com/reaction/403965

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 1-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)cyclopentanecarboxylateHCID 67305539—
Reactant(R)-3-Methyl-2-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)butanoic acidHCID 67308300—
Product1-(1-Oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)cyclopentanecarboxylic acidHCID 6730648783%

Reaction Steps

The compound of example 370 was prepared analogous to the compound of example 361 by hydrolysis of the compound of example 369.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-98f357c2c896416c93dc201c37b3b93b
Source noteuspto-grants-2014_06