HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-Methyl-2-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)butanoic acid → (S)-2-(1-Oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)-3-phenylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-Methyl-2-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)butanoic acid | HCID 67308300 | — |
| Reactant | (S)-Methyl 2-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)-3-phenylpropanoate | HCID 131731541 | — |
| Product | (S)-2-(1-Oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)-3-phenylpropanoic acid | HCID 67307308 | 87% |
Reaction Steps
The compound of example 382 was prepared analogous to the compound of example 361 by hydrolysis of the compound of example 381.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-28426593db674f869a8486b4e35eed48 |
| Source note | uspto-grants-2014_06 |