HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chloro-2-phenoxyphenyl isocyanate → (S)-Methyl 2-(6-(5-(3-(4-chloro-2-phenoxyphenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chloro-2-phenoxyphenyl isocyanate | HCID 3407433 | — |
| Edukt | (S)-Methyl 2-(6-(5-aminopyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731548 | — |
| Edukt | (S)-Methyl 2-(6-(5-(3-(2-chlorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731549 | — |
| Produkt | (S)-Methyl 2-(6-(5-(3-(4-chloro-2-phenoxyphenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 53302548 | — |
Reaktionsschritte
The compound of example 395 was prepared analogous to the compound of example 393 by reaction of the compound of example 392 with 4-chloro-2-phenoxy phenyl isocyanate. The compound of example 395 was used directly for the preparation of compound of example 396 without purification.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08748426B2 |
| Quelldatensatz | uspto-grants-2014_06 |
| ORD ID | ord-926b1bc0a62943419c5534de587990fb |
| Quellennotiz | uspto-grants-2014_06 |