(S)-2-(6-(5-(4-tert-Butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid → (S)-3-Methyl-2-(1-oxo-6-(4-(4-pentylbenzamido)-2-(trifluoromethyl)phenyl)isoindolin-2-yl)butanoic acid

Participants

Role	Name	HCID	Charge
Reactant	(S)-2-(6-(5-(4-tert-Butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid	HCID 67306402	—
Reactant	(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(4-pentylbenzamido)-2-(trifluoromethyl)phenyl)isoindolin-2-yl)butanoate	HCID 123601898	—
Product	(S)-3-Methyl-2-(1-oxo-6-(4-(4-pentylbenzamido)-2-(trifluoromethyl)phenyl)isoindolin-2-yl)butanoic acid	HCID 70975293	79%

The compound of example 430 was prepared analogous to the compound of example 404 by hydrolysis of the compound of example 429.