HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butylbenzoyl chloride → (S)-Methyl 2-(6-(4-(4-tert-butylbenzamido)-2-methylphenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butylbenzoyl chloride | HCID 74372 | — |
| Reactant | (S)-Methyl 2-(6-(5-(4-tert-butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731552 | — |
| Product | (S)-Methyl 2-(6-(4-(4-tert-butylbenzamido)-2-methylphenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123966518 | 82% |
Reaction Steps
The compound of example 467 was prepared analogous to the compound of example 403 by reaction of the compound of example 466 with 4-(t-butyl)benzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-e2bf90ef127e4345bb99e57cb7d921ad |
| Source note | uspto-grants-2014_06 |