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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404021Generated: October 29, 2026

(S)-2-(6-(5-(4-tert-Butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid → (S)-2-(6-(4-(4-tert-Butylbenzamido)-2-methylphenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid

https://huagongshe.com/reaction/404021

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(6-(5-(4-tert-Butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acidHCID 67306402—
Reactant(S)-Methyl 2-(6-(4-(4-tert-butylbenzamido)-2-methylphenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123966518—
Product(S)-2-(6-(4-(4-tert-Butylbenzamido)-2-methylphenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acidHCID 6730561482%

Reaction Steps

The compound of example 468 was prepared analogous to the compound of example 404 by hydrolysis of the compound of example 467.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-c40df20e187a4aa89e4fadb5408dc2e3
Source noteuspto-grants-2014_06