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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404038Generated: October 25, 2026

Methyl 2-methyl-2-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)propanoate → Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-2-methylpropanoate

https://huagongshe.com/reaction/404038

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-methyl-2-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)propanoateHCID 67306803—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
ProductMethyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-2-methylpropanoateHCID 6730752878%

Reaction Steps

The compound of example 515 was prepared analogous to the compound of example 6 by reduction of the compound of example 514.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-4bc037e6d990495886e9e3cc6a423664
Source noteuspto-grants-2014_06