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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404089Generated: October 29, 2026

Ethyl 5-phenyl-1,3-oxazole-2-carboxylate → (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(5-phenyloxazole-2-carboxamido)phenyl)isoindolin-2-yl)butanoate

https://huagongshe.com/reaction/404089

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-phenyl-1,3-oxazole-2-carboxylateHCID 13388477—
Reactant(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(5-phenylthiazole-2-carboxamido)phenyl)isoindolin-2-yl)butanoateHCID 123332092—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
Product(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(5-phenyloxazole-2-carboxamido)phenyl)isoindolin-2-yl)butanoateHCID 123818773—

Reaction Steps

The compound of example 613 was prepared analogous to the compound of example 611 by reaction of compound of example 6 with ethyl 5-phenyloxazole-2-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-00e74638b2524de492e2dc5a259388af
Source noteuspto-grants-2014_06