Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Tri-o-tolylphosphine | HCID 80271 | — |
| Reactant | HCID 131731596 | HCID 131731596 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Product | HCID 59364492 | HCID 59364492 | — |
Reaction Steps
7.00 g of 4-oxo-24(E)-propenyl)-6-(tetrahydropyran-2-yloxymethyl)-4H-pyran-3-yl trifluoromethanesulfonate were dissolved in 40.8 ml of DMF, and 75.8 mg of palladium(II) acetate, 154 mg of tri-(o-tolyl)-phosphine, 7.07 ml of triethylamine and 0.64 ml of formic acid were added. The reaction mixture was heated at 60° C. for 1 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08748483B2 |
|---|
| Source dataset | uspto-grants-2014_06 |
|---|
| ORD ID | ord-a400190eb793462abc9ef9f2f89730cb |
|---|
| Source note | uspto-grants-2014_06 |
|---|
