HRID404553

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID16988

2,3-Dichloropyridine

C5H3Cl2N

HCID7330434

2-Methylpiperazine, (R)-

C5H12N2

HCID12488883

3-(Trimethylsilyl)aniline

C9H15NSi

PRODUCTS

生成物

HCID22727561

未命名化合物

收率 93.2%

PROCEDURE

实验过程

Compound A-02 can be synthesized according to method 1. Just R1, R2, and R3 of Scheme 1 are respectively —Cl, -Me and p-SiMe3. More specifically, compound 1 is 2,3-dichloro-pyridine (6 g), compound 2 is (R)-2-methylpiperazine, the synthesized compound 3 is 1-(3-chloro-2-pyridyl)-3-methyl-piperazine (38 g, yield about 93.2%).

WORKUP

后处理

customCompound A-02 can be synthesized