6-Bromo-2-[(4-methoxyphenyl)methyl]-1(2H)-isoquinolinone → 6-Bromo-7-chloro-2-(4-methoxy-benzyl)-2H-isoquinolin-1-one

Participants

Role	Name	HCID	Charge
Reactant	6-Bromo-2-[(4-methoxyphenyl)methyl]-1(2H)-isoquinolinone	HCID 57551771	—
Reactant	6-Bromo-7-chloro-1,2-dihydroisoquinolin-1-one	HCID 59226278	—
Product	6-Bromo-7-chloro-2-(4-methoxy-benzyl)-2H-isoquinolin-1-one	HCID 59226259	—

Reaction Steps

Starting from 6-Bromo-7-chloro-2H-isoquinolin-1-one (12), the title compound was prepared by the method described for 6-Bromo-2-(4-methoxy-benzyl)-2H-isoquinolin-1-one (compound 13). Rt=2.12 min (Method B). Detected mass: 378.1/380.1 (M+H+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08748614B2
Source dataset	uspto-grants-2014_06
ORD ID	ord-251e16e724134b19a8a1c48725ac46ed
Source note	uspto-grants-2014_06