Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404733Generated: October 26, 2026

6-Bromo-7-chloroisoquinoline → 6-Bromo-7-chloro-2-(4-methoxy-benzyl)-2H-isoquinolin-1-one

https://huagongshe.com/reaction/404733

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromo-7-chloroisoquinolineHCID 53418615—
Reactant6-Bromo-2-[(4-methoxyphenyl)methyl]-1(2H)-isoquinolinoneHCID 57551771—
Product6-Bromo-7-chloro-2-(4-methoxy-benzyl)-2H-isoquinolin-1-oneHCID 59226259—

Reaction Steps

Starting from 6-Bromo-7-chloro-isoquinoline (263), the title compound was prepared by the method described for 6-Bromo-2-(4-methoxy-benzyl)-2H-isoquinolin-1-one (13). Rt=1.66 min (Method C). Detected mass: 318.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748614B2
Source datasetuspto-grants-2014_06
ORD IDord-6fa36d25e0454c5bb92cd593d6d543f1
Source noteuspto-grants-2014_06