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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404745Generated: October 30, 2026

Hydrochloric Acid → HCID 68592745, compound

https://huagongshe.com/reaction/404745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 68593037HCID 68593037—
SolventIsopropanolHCID 3776—
ProductHCID 68592745HCID 68592745—

Reaction Steps

85 mg (107 mmol) 4-(7-Propyl-isoquinolin-6-ylsulfanyl)-piperidine-1-carboxylic acid tert-butyl ester trifluoroacetate (276) were stirred in 6N HCl in iPrOH for 1 h at RT. After evaporation water was added and lyophilized. 42 mg of 6-(Piperidin-4-ylsulfanyl)-7-propyl-isoquinoline hydrochloride were obtained. Rt=0.94 min (Method B). Detected mass: 287.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748614B2
Source datasetuspto-grants-2014_06
ORD IDord-dfbc78cd55084523bdec11183235ce9c
Source noteuspto-grants-2014_06